top of page
Publications: Publications



Growth and Form

Hôpital Universitaire
Necker - Enfants Malades

Chiari malformation type I surgery in children: French multicenter 10-year cohort

Mazerand E, Benichi S, Taverne M, Paternoster G, Rolland A, Antherieu P, Todeschi J, Kamdem Noumoye L, Gilard V, Bretonnier M, Le Fournier L, Jecko V, Gimbert E, Proust F, Boetto S, Roujeau T, James S, Khonsari RH, Riffaud L, Delion M, Zerah M, Scavarda D.

doi link :

June 2022

FGFR3 overactivation in the brain is responsible for memory impairments in Crouzon syndrome mouse model

Cornille M, Moriceau S, Khonsari RH, Heuzé Y, Loisay L, Boitez V, Morice A, Arnaud E, Collet C, Bensidhoum M, Kaci N, Boddaert N, Paternoster G, Rauschendorfer T, Werner S, Mansour SL, Di Rocco F, Oury F, Legeai-Mallet L.

J Exp Med. 2022 Apr 4;219(4):e20201879. doi: 10.1084/jem.20201879. Epub 2022 Mar 7. PMID: 35254402.

March 2022

Convolutional mesh autoencoders for the 3-dimensional identification of FGFR-related craniosynostosis

O' Sullivan E, van de Lande LS, Papaioannou A, Breakey RWF, Jeelani NO, Ponniah A, Duncan C, Schievano S, Khonsari RH, Zafeiriou S, Dunaway DJ

Sci Rep. 2022 Feb 9;12(1):2230. doi: 10.1038/s41598-021-02411-y. PMID: 35140239; PMCID: PMC8828904.

Feb. 2022

Scaphocephaly and increased intra-cranial pressure in non-operated adults: A controlled anthropological study on 21 skulls

Delattre MH, Hennocq Q, Stricker S, Paternoster G, Khonsari RH.

J Stomatol Oral Maxillofac Surg. 2022 Feb

4:S2468-7855(22)00029-5. doi: 10.1016/j.jormas.2022.01.012. Epub ahead of print.

PMID: 35131525.

Feb. 2022

Ophthalmological findings in children with unicoronal craniosynostosis

Touzé R, Paternoster G, Arnaud E, Khonsari RH, James S, Bremond-Gignac D, Robert MP.

Eur J Ophthalmol. 2022 Feb 4:11206721221077548. doi: 10.1177/11206721221077548. Epub ahead of print. PMID: 35118895.

Feb. 2022

Paediatric skull growth models: A systematic review of applications to normal skulls and craniosynostoses

Geoffroy M, François PM, Khonsari RH, Laporte S.

J Stomatol Oral Maxillofac Surg. 2022 Jan

7:S2468-7855(22)00002-7. doi: 10.1016/j.jormas.2022.01.002. Epub ahead of print.

PMID: 35007781.

Jan. 2022

The 3D skull 0–4 years: A validated, generative, statistical shape model

O' Sullivan E, van de Lande LS, Oosting AC, Papaioannou A, Jeelani NO,

Koudstaal MJ, Khonsari RH, Dunaway DJ, Zafeiriou S, Schievano S.

Bone Rep. 2021 Nov 29;15:101154. doi: 10.1016/j.bonr.2021.101154. PMID: 34917697; PMCID: PMC8645852.

Dec. 2021

Dental phenotype in Crouzon syndrome: A controlled radiographic study in 22 patients

Sicard L, Hennocq Q, Paternoster G, Arnaud E, Dure-Molla M, Khonsari RH. 

Arch Oral Biol. 2021 Nov;131:105253. doi:

10.1016/j.archoralbio.2021.105253. Epub 2021 Sep 3. PMID: 34500259.

Nov. 2021

Predicting and comparing three corrective techniques for sagittal craniosynostosis.

Cross C, Khonsari RH, Larysz D, Johnson D, Kölby L, Moazen M. 

Sci Rep. 2021 Oct 27;11(1):21216. doi: 10.1038/s41598-021-00642-7. PMID: 34707183; PMCID: PMC8551239.

Oct. 2021

In-house 3D printing: Why, when, and how? Overview of the national French good practice guidelines for in-house 3D-printing in maxillo-facial surgery, stomatology, and oral surgery

Khonsari RH, Adam J, Benassarou M, Bertin H, Billotet B, Bouaoud J, Bouletreau P, Garmi R, Gellée T, Haen P, Ketoff S, Lescaille G, Louvrier A, Lutz

JC, Makaremi M, Nicot R, Pham-Dang N, Praud M, Saint-Pierre F, Schouman T, Sicard L, Simon F, Wojcik T, Meyer C; French Society of Stomatology, Maxillo- Facial Surgery and Oral Surgery (SFSCMFCO)

J Stomatol Oral Maxillofac Surg. 2021 Sep;122(4):458-461. doi: 10.1016/j.jormas.2021.08.002. Epub 2021 Aug 13. PMID: 34400375.

Sept. 2021

Computational diagnostic methods on 2D photographs: A review of the literature

Hennocq Q, Khonsari RH, Benoît V, Rio M, Garcelon N.

J Stomatol Oral Maxillofac Surg. 2021 Sep;122(4):e71-e75. doi: 10.1016/j.jormas.2021.04.003. Epub 2021 Apr 20. PMID: 33848665.

Sept. 2021

DIVA, a 3D virtual reality platform, improves undergraduate craniofacial trauma education.

Bouaoud J, El Beheiry M, Jablon E, Schouman T, Bertolus C, Picard A, Masson JB, Khonsari RH.

J Stomatol Oral Maxillofac Surg 2020;S2468-7855(20)30221-4. doi: 10.1016/j.jormas.2020.09.009.

Sept. 2021

Using Sensitivity Analysis to Develop a Validated Computational Model of Post-operative Calvarial Growth in Sagittal Craniosynostosis

Cross C, Khonsari RH, Galiay L, Patermoster G, Johnson D, Ventikos Y, MoazenM.

Front Cell Dev Biol. 2021 May 26;9:621249. doi: 10.3389/fcell.2021.621249. PMID: 34124030; PMCID: PMC8187911.

May 2021

Early mandibular morphological differences in patients with FGFR2 and FGFR3-related syndromic craniosynostoses: A 3D comparative study.

Morice A, Cornette R, Giudice A, Collet C, Paternoster G, Arnaud É, Galliani E, Picard A, Legeai-Mallet L, Khonsari RH.

Bone 2020;141:115600. doi: 10.1016/j.bone.2020.115600.

Dec. 2020

Twelve-year experience in mandibular reconstruction using osteo-muscular dorsal scapular pedicled flaps

Hennocq Q, Khonsari RH, Vacher C, Nicol P.

Plast Reconstr Aesthet Surg. 2021 Feb;74(2):259-267. doi: 10.1016/j.bjps.2020.08.124. Epub 2020 Sep 20. PMID: 33127348.

Sept. 2020

The influence of fronto-facial monobloc advancement on obstructive sleep apnea: An assessment of 109 syndromic craniosynostoses cases.

Khonsari RH, Haber S, Paternoster G, Fauroux B, Morisseau-Durand MP, Cormier-Daire V, Legeai-Mallet L, James S, Hennocq Q, Arnaud E.

J Craniomaxillofac Surg 2020;48(6):536-547. doi: 10.1016/j.jcms.2020.04.001.

June 2020

Nasal cavity shape in unilateral choanal atresia and the role of fetal ventilation in facial growth.

Ferrier S, Hennocq Q, Leboulanger N, Couloigner V, Denoyelle F, Heuzé Y, Khonsari RH.

J Stomatol Oral Maxillofac Surg 2020:S2468-7855(20)30140-3. doi: 10.1016/j.jormas.2020.05.021.

April 2020

Excessive ossification of the bandeau in Crouzon and Apert syndromes.

Bouaoud J, Hennocq Q, Paternoster G, James S, Arnaud E, Khonsari RH.

J Craniomaxillofac Surg 2020;48(4):376-382. doi: 10.1016/j.jcms.2020.02.022.

April 2020

Maxillary shape at the end of puberty in operated unilateral cleft lip and palate: A geometric morphometric assessment using computer tomography.

Segna E, Khonsari RH, Meazzini MC, Battista VMA, Picard A, Autelitano L.

J Stomatol Oral Maxillofac Surg 2020;121(1):9-13. doi: 10.1016/j.jormas.2019.06.004.

Feb. 2020

Extraocular muscle positions in anterior plagiocephaly: V-pattern strabismus explained using geometric mophometrics.

Touzé R, Heuzé Y, Robert MP, Brémond-Gignac D, Roux CJ, James S, Paternoster G, Arnaud E, Khonsari RH.

Br J Ophthalmol 2020;104(8):1156-1160. doi: 10.1136/bjophthalmol-2019-314989.


Defining critical ages for orbital shape changes after frontofacial advancement in Crouzon syndrome.

Khonsari RH, Hennocq Q, Nysjö J, Sandy R, Haber S, James S, Britto JA, Paternoster G, Arnaud É.

Plast Reconstr Surg 2019;144(5):841e-852e. doi: 10.1097/PRS.0000000000006162.

Nov. 2019

Maxillary shape after primary cleft closure and before alveolar bone graft in two different management protocols: A comparative morphometric study.

Girinon F, Ketoff S, Hennocq Q, Kogane N, Ullman N, Kadlub N, Galliani E, Neiva-Vaz C, Vazquez MP, Picard A, Khonsari RH.

J Stomatol Oral Maxillofac Surg 2019;120(5):406-409. doi: 10.1016/j.jormas.2019.02.001.

Nov. 2019

Craniofacial bone atrophy in Parry Romberg syndrome demonstrated using a Bayesian hierarchical model.

Hennocq Q, Facchini A, Kverneland B, Bodemer C, Picard A, Khonsari RH.

J Craniomaxillofac Surg 2019;47(6):909-914. doi: 10.1016/j.jcms.2019.03.032.

June 2019

Correcting Exorbitism by Monobloc Frontofacial Advancement in Crouzon-Pfeiffer Syndrome: An Age-Specific, Time-Related, Controlled Study.

Way BLM, Khonsari RH, Karunakaran T, Nysjö J, Nyström I, Dunaway DJ, Evans RD, Hayward RD, Britto JA.

Plast Reconstr Surg 2019;143(1):121e-132e. doi: 10.1097/PRS.0000000000005105.

Jan. 2019

Dental consequences of pterygomaxillary dysjunction during fronto-facial monobloc advancement with internal distraction for Crouzon syndrome.

Sicard L, Hounkpevi M, Tomat C, James S, Paternoster G, Khonsari RH, Arnaud E.

J Craniomaxillofac Surg 2018;46(9):1476-1479. doi: 10.1016/j.jcms.2018.06.003.

Sept. 2018

Orbital shape in intentional skull deformations and adult sagittal craniosynostoses.

Sandy R, Hennocq Q, Nysjö J, Giran G, Friess M, Khonsari RH.

J Anat 2018;233(3):302-10. doi: 10.1111/joa.12844.

June 2018

Anterior skull base and pericranial flap ossification after frontofacial monobloc advancement.

Morice A, Paternoster G, Ostertag A, James S, Cohen-Solal M, Khonsari RH, Arnaud E.

Plast Reconstr Surg 2018;141(2):437-445. doi: 10.1097/PRS.0000000000004040.

Feb. 2018

Orbital volume and shape in Treacher Collins syndrome.

Levasseur J, Nysjö J, Sandy R, Britto JA, Garcelon N, Haber S, Picard A, Corre P, Odri GA, Khonsari RH.

J Craniomaxillofac Surg 2018;46(2):305-311. doi: 10.1016/j.jcms.2017.11.028.

Feb. 2018

Quantitative assessment of the learning curve for cleft lip repair using LC-CUSUM.

Segna E, Caruhel JB, Corre P, Picard A, Biau D, Khonsari RH.

Int J Oral Maxillofac Surg 2018;47(3):366-373. doi: 10.1016/j.ijom.2017.10.005.

Oct. 2017

Modelling human skull growth:
A validated computational model.

Libby J, Marghoub A, Johnson D, Khonsari RH, Fagan MJ, Moazen M.

J R Soc Interface 2017;14(130):20170202. doi: 10.1098/rsif.2017.0202.

May. 2017

Zygomatic bone shape in intentional cranial deformations: a model for the study of the interactions between skull growth and facial morphology.

Ketoff S, Girinon F, Schlager S, Friess M, Schouman T, Rouch P, Khonsari RH.

J Anat 2017;230(4):524-531. doi: 10.1111/joa.12581.

Dec. 2016

Fronto-facial advancement and bipartition in Crouzon-Pfeiffer and Apert syndromes: Impact of fronto-facial surgery upon orbital and airway parameters in FGFR2 syndromes.

Khonsari RH, Way B, Nysjö J, Odri GA, Olszewski R, Evans RD, Dunaway DJ, Nyström I, Britto JA.

J Craniomaxillofac Surg 2016;44(10):1567-1575. doi: 10.1016/j.jcms.2016.08.015.

Oct. 2016

Submicron imaging of soft-tissues using low-dose phase-contrast
x-ray synchrotron microtomography with an iodine contrast agent.

Khonsari RH, Healy C, Ohazama A, Sharpe PT, Dutel H, Charles C, Viriot L, Tafforeau P.

Anat Rec 2014;297(10):1803-7. doi: 10.1002/ar.22997.

July 2014

Shape and volume of craniofacial cavities in intentional skull deformations.

Khonsari RH, Friess M, Nysjö J, Odri G, Malmberg F, Nyström I, Messo E, Hirsch JM, Cabanis EA, Kunzelmann KH, Salagnac JM, Corre P, Ohazama A, Sharpe PT, Charlier P, Olszewski R.

Am J Phys Anthropol 2013;151(1):110-9. doi: 10.1002/ajpa.22263.

March 2013

A mathematical model for mechanotransduction at the early steps of suture formation.

Khonsari RH, Olivier J, Vigneaux P, Sanchez S, Tafforeau P, Ahlberg PE, Di Rocco F, Bresch D, Corre P, Ohazama A, Sharpe PT, Calvez V.

Proc Biol Sci 2013;280(1759):20122670. doi: 10.1098/rspb.2012.2670.

May 2013

Multiple postnatal craniofacial anomalies are characterized by conditional loss of polycystic kidney disease 2 (Pkd2).

Khonsari RH, Ohazama A, Raouf R, Kawasaki M, Kawasaki K, Porntaveetus T, Ghafoor S, Hammond P, Suttie M, Odri GA, Sandford RN, Wood JN, Sharpe PT.

Hum Mol Genet 2013;22(9):1873-85. doi: 10.1093/hmg/ddt041.

May 2013

The buccohypophyseal canal is an ancestral vertebrate trait maintained by modulation in sonic hedgehog signaling.

Khonsari RH, Seppala M, Pradel A, Dutel H, Clément G, Lebedev O, Ghafoor S, Rothova M, Tucker A, Maisey JG, Fan CM, Kawasaki M, Ohazama A, Tafforeau P, Franco B, Helms J, Haycraft CJ, David A, Janvier P, Cobourne MT, Sharpe PT.

BMC Biol 2013;11:27. doi: 10.1186/1741-7007-11-27.

March 2013

Central nervous system malformations and deformations in FGFR2-related craniosynostosis.

Khonsari RH, Delezoide AL, Kang W, Hébert JM, Bessières B, Bodiguel V, Collet C, Legeai-Mallet L, Sharpe PT, Fallet-Bianco C.

Am J Med Genet A 2012;158A(11):2797-806. doi: 10.1002/ajmg.a.35598.

Sept. 2012

High-resolution imaging of craniofacial sutures: new tools for understanding the origins of craniosynostoses.

Khonsari RH, Di Rocco F, Arnaud E, Sanchez S, Tafforeau P.

Childs Nerv Syst 2012;28(9):1465-9. doi: 10.1007/s00381-012-1794-9.

Aug. 2012

bottom of page